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Glutathione influences this process in three distinct ways: Inhibition of Tyrosinase: Tyrosinase is the rate-limiting enzyme in the production of melanin

It also has direct effects on glucose body function, tending to increase blood glucose through insulin antagonism

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Kasperczyk S, Dobrakowski M, Kasperczyk A, Ostalowska A, Birkner E (2013) The administration of N-acetylcysteine reduces oxidative stress and regulates glutathione metabolism in the blood cells of workers exposed to lead